Amos Arieli , Dept. of Neurobiology, The Weizmann Institute of Science

room 1061, Meyer building, Electrical Engineering at 16:00

31 May, 2011

Ongoing Dynamics and Brain Connectivity: From Intracellular Recordings to Human Neurophysiology


What is the temporal precision of cortical activity?  It is clear that the wide range of coding schemes occur on different time scales: Millisecond scale characterizes direct sensory events, tens to hundreds of milliseconds scale characterizes attention processes, while different states of alertness can last many seconds. It seems that there is a direct relationship between the time scale and the spatial resolution in cortical activity. The activity involved in a direct sensory process is well defined in small areas; for example an orientation column. On the other hand an attention process involves huge populations and maybe even the whole cortex.

In my talk I will try to bridge the gap between the recordings of single neurons (intracellular and extracellular recordings) and the recordings of large populations of neurons (EEG, LFP,VSD or fMRI) in order to understand the spatio-temporal organization underlying the function of cortical neuronal population and it's relation to brain connectivity.

I will relate to the following topics:
-    What is the size of the neuronal population that contributes to the population activity in different cognitive states?
-    What is the degree of synchronization within this population?
-    What is the relationship between the population activity and the activity of single cortical neurons?
-    The dynamic of coherent activity in neuronal assemblies - ongoing & evoked activity

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